The New York Times has an unenthusiastic review. 1000 Misspent Hours calls it one of the "precious few intelligent Frankenstein movies". Moria says,
This is where it all began – the grand Anglo-horror cycle that lasted throughout the 1960s and most of the 1970s and had influences that reach to the continental Gothic horror revival of the 1960s and Roger Corman’s Edgar Allan Poe films. But most of all The Curse of Frankenstein is the beginning of the legend of Hammer Films.