Ark

The Ark is a 2007 animated science fiction short film directed by Grzegorz Jonkajtys.

from the director's web site:

An unknown virus has destroyed almost the entire human population. Oblivious to the true nature of the disease, the only remaining survivors escape to the sea. In great ships, they set off in search of uninhabited land. So begins the exodus, led by one man ...

There's a lot to think about here.

via youtube:

Animation Blog calls it "an inspiring example of the detail animation can obtain." Animation World Network notes: ""Ark" received a Golden Palm nomination at the Cannes Film Festival, an Award of Distinction at Prix Ars Electronica, and a Best in Show Award at SIGGRAPH." Computer Graphics World has some information on how the film was made.